Last data update: May 13, 2024. (Total: 46773 publications since 2009)
Records 1-4 (of 4 Records) |
Query Trace: Ledford K[original query] |
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Clostridium perfringens infections initially attributed to norovirus, North Carolina, USA, 2010
Dailey NJ , Lee N , Fleischauer AT , Moore ZS , Alfano-Sobsey E , Breedlove F , Pierce A , Ledford S , Greene S , Gomez GA , Talkington DF , Sotir MJ , Hall AJ , Sweat D . Clin Infect Dis 2012 55 (4) 568-70 We investigated an outbreak initially attributed to norovirus; however, Clostridium perfringens toxicoinfection was subsequently confirmed. C. perfringens is an underrecognized but frequently observed cause of foodborne disease outbreaks. This investigation illustrates the importance of considering epidemiologic and laboratory data together when evaluating potential etiologies that might require unique control measures. |
Norovirus outbreak associated with undercooked oysters and secondary household transmission
Alfano-Sobsey E , Sweat D , Hall A , Breedlove F , Rodriguez R , Greene S , Pierce A , Sobsey M , Davies M , Ledford SL . Epidemiol Infect 2012 140 (2) 276-82 During December 2009, over 200 individuals reported gastrointestinal symptoms after dining at a North Carolina restaurant. An outbreak investigation included a case-control study of restaurant patrons, a secondary household transmission study, environmental assessment of the restaurant facilities and operations, and laboratory analysis of stool and food samples. Illness was primarily associated with consumption of steamed oysters (odds ratio 12, 95% confidence interval 4.8-28) and 20% (8/41 households) reported secondary cases, with a secondary attack rate of 14% among the 70 susceptible household contacts. Norovirus RNA was detected in 3/5 stool specimens from ill patrons; sequencing of RT-PCR products from two of these specimens identified identical genogroup II genotype 12 sequences. Final cooked temperatures of the steamed oysters were generally inadequate to inactivate norovirus, ranging from 21 degrees C to 74 degrees C. Undercooked contaminated oysters pose a similar risk for norovirus illness as raw oysters and household contacts are at risk for secondary infection. |
Choropleth map design for cancer incidence, part 1
Richards TB , Berkowitz Z , Thomas CC , Foster SL , Gardner A , King JB , Ledford K , Royalty J . Prev Chronic Dis 2010 7 (1) A23 Choropleth maps are commonly used in cancer reports and community discussions about cancer rates. Cancer registries increasingly use geographic information system techniques. The Centers for Disease Control and Prevention's Division of Cancer Prevention and Control convened a Map Work Group to help guide application of geographic information systems mapping techniques and to promote choropleth mapping of data from central cancer registries supported by the National Program of Cancer Registries, especially for planning and evaluation of comprehensive cancer control programs. In this 2-part series in this issue of Preventing Chronic Disease, we answer frequently asked questions about choropleth map design to display cancer incidence data. We recommend that future initiatives consider more advanced mapping, spatial analysis, and spatial statistics techniques, and include usability testing with representatives of state and local programs and other cancer prevention partners. |
Choropleth map design for cancer incidence, part 2
Richards TB , Berkowitz Z , Thomas CC , Foster SL , Gardner A , King JB , Ledford K , Royalty J . Prev Chronic Dis 2010 7 (1) A24 Choropleth maps are commonly used in cancer reports and community discussions about cancer rates. Cancer registries increasingly use geographic information system techniques. The Centers for Disease Control and Prevention's Division of Cancer Prevention and Control convened a Map Work Group to help guide application of geographic information system mapping techniques and to promote choropleth mapping of data from central cancer registries supported by the National Program of Cancer Registries, especially for comprehensive cancer control planning and evaluation purposes. In this 2-part series, we answer frequently asked questions about choropleth map design to display cancer incidence data. We recommend that future initiatives consider more advanced mapping, spatial analysis, and spatial statistics techniques and include usability testing with representatives of state and local programs and other cancer prevention partners. |
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